LIG4 syndrome

Orpha code: 99812OMIM code: 606593

Definition

LIG4 syndrome is a hereditary disorder associated with impaired DNA double-strand break repair mechanisms and characterized by microcephaly, unusual facial features, growth and developmental delay, skin anomalies, and pancytopenia, which is associated with combined immunodeficiency (CID).

Disease data
Classification

Disease

Synonyms
DNA ligase IV deficiency
Niedobór ligazy DNA IV
Zespół ligazy 4
Ligase 4 syndrome
ORPHA code
99812
OMIM code
606593
ICD10 code
D81.1
ICD11 code
-

No additional description.

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