Adenine phosphoribosyltransferase deficiency

Orpha code: 976OMIM code: 614723

Definition

A rare genetic nephropathy secondary to a disorder of purine metabolism characterized by the formation and hyperexcretion of 2,8-dihydroxyadenine (2,8-DHA) in urine, causing urolithiasis and crystalline nephropathy.

Disease data
Classification

Disease

Synonyms
2,8-dihydroxyadenine urolithiasis
Kamica 2,8 dihydroksyadeninowa
Niedobór APRT
Niedobór fosforybozylotransferazy adeninowej
APRT deficiency
ORPHA code
976
OMIM code
614723
ICD10 code
E79.8
ICD11 code
5C55.0Y

No additional description.

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