AL amyloidosis

Orpha code: 85443OMIM code: 254500

Definition

A clonal B-cell disorder characterized by the aggregation and deposition of insoluble amyloid fibrils derived from misfolding of monoclonal immunoglobulin light chains. It usually presents as systemic AL amyloidosis with involvement of one or more parenchymal organ(s) and, less frequently, as localized amyloidosis with usually nodular deposits restricted to a single organ and/or system.

Disease data
Classification

Disease

Synonyms
Light-chain amyloidosis
Amyloidoza immunoglobulinowa
Amyloidoza łańcuchów lekkich
Amyloidoza pierwotna
Primary amyloidosis
ORPHA code
85443
OMIM code
254500
ICD10 code
E85.9
ICD11 code
5D00.0

No additional description.

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