Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition Palmoplantar keratoderma-XX sex reversal-predisposition to squamous cell carcinoma syndrome is characterised by sex reversal in males with a 46, XX (SRY-negative) karyotype, palmoplantar hyperkeratosis and a predisposition to squamous cell carcinoma. To date, five cases (four of whom were brothers) have been described. The aetiology is unknown. Disease data Classification Disease Synonyms Palmoplantar hyperkeratosis-XX sex reversal-predisposition to squamous cell carcinoma syndrome Hiperkeratoza dłoni i stóp - odwrócenie płci XX - predyspozycja do raka kolczystokomórkowego ORPHA code 85112 OMIM code 610644 ICD10 code Q56.0 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl