Schizencephaly

Definition

A rare developmental defect during embryogenesis characterized by the presence of linear clefts containing cerebrospinal fluid lined by abnormal grey matter that extend from the lateral ventricles to the pial surface of the cortex. Schizencephaly can involve one or both cerebral hemispheres and may lead to a variety of neurological symptoms such as epilepsy, motor deficits, and psychomotor retardation.

Disease data

Classification

Disease

ORPHA code

799

OMIM code

269160

ICD10 code

Q04.6

ICD11 code

LA05.61

*Soruce