46,XY difference of sex development due to 5-alpha-reductase 2 deficiency

Orpha code: 753OMIM code: 264600

Definition

A rare disorder of sex development (DSD) due to a defect in metabolizing testosterone to dihydrotestosterone and characterized by incomplete intrauterine masculinization which ranges from a female genitalia with a blind vaginal pouch to a fully male phenotype with pseudovaginal posterior hypospadias and micropenis.

Disease data
Classification

Disease

Synonyms
46,XY DSD due to 5-alpha-reductase 2 deficiency
Niedobór 5-alfa-reduktazy steroidowej
Pseudohermafrodytyzm męski spowodowany niedoborem 5-alfa-reduktazy 2
ZRP 46,XY spowodowane niedoborem 5-alfa-reduktazy 2
Pseudovaginal perineoscrotal hypospadias
Steroid 5-alpha-reductase 2 deficiency
46,XY disorder of sex development due to 5-alpha-reductase 2 deficiency
ORPHA code
753
OMIM code
264600
ICD10 code
E29.1
ICD11 code
LD2A.3

No additional description.

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