Hyperinsulinism due to short chain 3-hydroxylacyl-CoA dehydrogenase deficiency

Orpha code: 71212OMIM code: 609975

Definicja

A rare form of congenital diazoxide-sensitive diffuse hyperinsulinism due to short chain 3 hydroxylacyl-CoA dehydrogenase (SCHAD; <i>HADH</i> gene) deficiency and characterized by hyperinsulinemic hypoglycemia with seizures and reported to respond well to diazoxide. It presents with the classical manifestations of hyperinsulinemic hypoglycemia. Exceptional complications include sudden death, and in one case fulminant hepatic failure.

Disease data
Klasyfikacja

Disease

Synonimy
Hyperinsulinemic hypoglycemia due to short chain 3-hydroxylacyl-CoA dehydrogenase deficiency
Niedobór SCHAD
Hiperinsulinizm spowodowany niedoborem SCHAD
Hiperinsulinizm spowodowany niedoborem glutamodehydrogenazy
Hiperinsulinizm spowodowany niedoborem dehydrogenazy krótkich łańcuchów 3-hydroksyacylo-CoA
Hyperinsulinism due to SCHAD deficiency
Hyperinsulinism due to glutamodehydrogenase deficiency
SCHAD deficiency
Hiperinsulinizm spowodowany niedoborem dehydrogenazy 3-hydroksyacyl-CoA
Kod ORPHA
71212
Kod OMIM
609975
Kod ICD10
E71.3
Kod ICD11
-

No additional description.

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