Ornithine transcarbamylase deficiency

Orpha code: 664OMIM code: 311250

Definition

A rare, genetic disorder of urea cycle metabolism and ammonia detoxification characterized by either a severe, neonatal-onset disease found mainly in males, or later-onset (partial) forms of the disease. Both present with episodes of hyperammonemia that can be fatal and which can lead to neurological sequelae.

Disease data
Classification

Disease

Synonyms
OCT deficiency
Niedobór karbamylotransferazy ornityny
Niedobór OCT
Niedobór OTC
OTC deficiency
Ornithine carbamoyltransferase deficiency
ORPHA code
664
OMIM code
311250
ICD10 code
E72.4
ICD11 code
5C50.AY

No additional description.

Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl