Mucopolysaccharidosis type 2

Orpha code: 580OMIM code: 309900

Definition

A lysosomal storage disease with multisystemic involvement leading to a massive accumulation of glycosaminoglycans and a wide variety of symptoms including distinctive coarse facial features, short stature, cardio-respiratory involvement and skeletal abnormalities. It manifests as a continuum varying from a severe form with neurodegeneration to an attenuated form without neuronal involvement.

Disease data
Classification

Disease

Synonyms
Hunter syndrome
MPS2
MPSII
Mukopolisacharydoza typu II
Niedobór 2-sulfatazy idorunianu
Zespół Huntera
Iduronate 2-sulfatase deficiency
MPS2
MPSII
Mucopolysaccharidosis type II
ORPHA code
580
OMIM code
309900
ICD10 code
E76.1
ICD11 code
5C56.31

No additional description.

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