Mucolipidosis type II

Orpha code: 576OMIM code: 252500

Definition

A rare, severe form of mucolipidosis characterized by growth retardation, skeletal abnormalities (dysostosis multiplex, craniosynostosis, contractures of the joints and osteopenia), facial dysmorphism, stiff skin, obstructive airway, cardiomegaly and severe global developmental delay.

Disease data
Classification

Disease

Synonyms
I-cell disease
Niedobór N-acetyloglukozamino-1-fosfotransferazy
Choroba "I-cell"
Mucolipidosis type II alpha/beta
N-acetylglucosamine 1-phosphotransferase deficiency
ORPHA code
576
OMIM code
252500
ICD10 code
E77.0
ICD11 code
5C56.20

No additional description.

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