Lesch-Nyhan syndrome

Orpha code: 510OMIM code: 308950

Definition

Lesch-Nyhan syndrome (LNS) is the most severe form of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency (see this term), a hereditary disorder of purine metabolism, and is associated with uric acid overproduction (UAO), neurological troubles, and behavioral problems.

Disease data
Classification

Disease

Synonyms
HPRT complete deficiency
Całkowity Niedobór fosforybozylotransferazy hipoksantynowo-guaninowej
Całkowity Niedobór HPRT
Niedobór fosforybozylotransferazy hipoksantynowo-guaninowej, IV stopnia
Niedobór HPRT IV stopnia
HPRT deficiency grade IV
Hypoxanthine guanine phosphoribosyltransferase complete deficiency
Hypoxanthine guanine phosphoribosyltransferase deficiency, grade IV
ORPHA code
510
OMIM code
308950
ICD10 code
E79.1
ICD11 code
5C55.01

No additional description.

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