Colobomatous macrophthalmia-microcornea syndrome

Orpha code: 468672OMIM code: 602499

Definition

A rare genetic eye disease characterized by microcornea, coloboma of the iris and the optic disc, axial enlargement of the globe, staphyloma, and severe myopia. Additional manifestations are mild cornea plana, iridocorneal angle abnormalities with elevation of intraocular pressure, and shallow anterior chamber depth. Variable expressivity of the phenotype has been described, including unilateral or bilateral involvement, or variable extent of coloboma, among other features.

Disease data
Classification

Disease

Synonyms
MACOM syndrome
Zespół MACOM
ORPHA code
468672
OMIM code
602499
ICD10 code
-
ICD11 code
-

No additional description.

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