ALECT2 amyloidosis

Orpha code: 439224OMIM code:

Definition

A rare, systemic amyloidosis characterized by slowly progressive renal disease presenting with proteinuria, hypertension and decreased glomerular filtration rate leading to progressive renal failure. Histology reveals amyloid deposits of leukocyte chemotactic factor-2 protein in the renal cortical interstitium, tubular basement membranes, glomeruli and the vessel walls. Extra-renal deposits can be seen in the liver, lungs, spleen and adrenal glands.

Disease data
Classification

Disease

Synonyms
Leukocyte chemotactic factor-2 amyloidosis
Amyloidoza czynnika-2 chemotaktycznego leukocytów
ORPHA code
439224
OMIM code
-
ICD10 code
E85.8
ICD11 code
-

No additional description.

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