Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition Bleeding disorder due to CalDAG-GEFI deficiency is a rare hematologic disease due to defective platelet function and characterized by mucocutaneous bleeding starting in infancy (around 18 months of age), presenting with prolonged and severe epistaxis, hematomas and bleeding after tooth extraction. Massive menorrhagia and chronic anemia have also been reported. Disease data Classification Disease Synonyms Bleeding disorder due to calcium- and DAG-regulated guanine exchange factor-1 deficiency Skaza krwotoczna z powodu niedoboru czynnika wymiany nukleotydów guaninowych-1 regulowanego wapniem i DAG ORPHA code 420566 OMIM code 615888 ICD10 code D69.1 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl