Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition COASY protein-associated neurodegeneration (CoPAN) is a very rare, slowly progressive form of neurodegeneration with brain iron accumulation (NBIA) characterized by classic NBIA features. The clinical manifestations include early-onset spastic-dystonic paraparesis, oromandibular dystonia, dysarthria, parkinsonism, axonal neuropathy, progressive cognitive impairment, complex motor tics, and obsessive-compulsive disorder. Disease data Classification Disease Synonyms CoPAN CoPAN NBIA6 Neurodegeneracja z magazynowaniem żelaza w mózgu z powodu mutacji COASY NBIA6 Neurodegeneration with brain iron accumulation due to COASY mutation ORPHA code 397725 OMIM code 615643 ICD10 code G23.0 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl