Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition Susceptibility to infection due to TYK2 deficiency is a rare primary immunodeficiency characterized by increased susceptibility to intracellular bacterial and viral infection, with or without increased serum IgE. Clinical manifestations are highly variable, depending on the infection type and location, and can include recurrent otitis, sinusitis, pulmonary and cutaneous infections, meningitis and internal abscesses. Disease data Classification Disease Synonyms Autosomal recessive hyper-IgE syndrome due to TYK2 deficiency AR-HIES z powodu niedoboru TYK2 Zespół AR-hyper IgE z powodu niedoboru TYK2 ORPHA code 331226 OMIM code 611521 ICD10 code D82.4 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl