Hairy cell leukemia variant

Orpha code: 300878OMIM code:

Definicja

A rare, malignant splenic B-cell lymphoma/leukemia characterized by circulating abnormal lymphocytes with intermediate morphology between prolymphocytes and hairy cells with positive expression of CD11c and negative expression of CD25, CD123 and the BRAFV600E mutation. Manifestations include splenomegaly, elevated white blood cell (WBC) count, hyper-cellular bone marrow and anemia/thrombocytopenia, but no monocytopenia.

Disease data
Klasyfikacja

Disease

Synonimy
HCL-v
HCL-v
Leukemic reticuloendotheliosis variant
Prolimfocytarny wariant białaczki włochatokomórkowej
Prolimfocytarny wariant HCL
Leukemic reticuloendotheliosis variant
Prolymphocytic variant of HCL
Prolymphocytic variant of hairy cell leukemia
Kod ORPHA
300878
Kod OMIM
-
Kod ICD10
C91.4
Kod ICD11
-

No additional description.

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