Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare, malignant splenic B-cell lymphoma/leukemia characterized by circulating abnormal lymphocytes with intermediate morphology between prolymphocytes and hairy cells with positive expression of CD11c and negative expression of CD25, CD123 and the BRAFV600E mutation. Manifestations include splenomegaly, elevated white blood cell (WBC) count, hyper-cellular bone marrow and anemia/thrombocytopenia, but no monocytopenia. Disease data Classification Disease Synonyms HCL-v HCL-v Leukemic reticuloendotheliosis variant Prolimfocytarny wariant białaczki włochatokomórkowej Prolimfocytarny wariant HCL Leukemic reticuloendotheliosis variant Prolymphocytic variant of HCL Prolymphocytic variant of hairy cell leukemia ORPHA code 300878 OMIM code - ICD10 code C91.4 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl