Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition Nasu-Hakola disease (NHD), also referred to as polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), is a rare inherited leukodystrophy characterized by progressive presenile dementia associated with recurrent bone fractures due to polycystic osseous lesions of the lower and upper extremities. Disease data Classification Malformation syndrome Synonyms NHD NHD plOSL plO-SL Wielotorbielowata tłuszczowo-błoniasta osteodysplazja ze stwardniajacą leukoencefalopatią PLO-SL PLOSL Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy ORPHA code 2770 OMIM code 221770 ICD10 code G31.8 ICD11 code 8A44.3 *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl