Hyperzincemia and hypercalprotectinemia

Orpha code: 251523OMIM code: 194470

Definicja

A rare inborn error of zinc metabolism characterized by recurrent infections, hepatosplenomegaly, anemia (unresponsive to iron supplementation) and chronic systemic inflammation in the presence of high plasma concentrations of zinc and calprotectin. Patients typically present dermal ulcers or other cutaneous manifestations (e.g. inflammation) and arthralgia. Severe epistaxis and spontaneous hematomas have also been reported.

Disease data
Klasyfikacja

Disease

Synonimy
Hz/Hc
PAMI syndrome
PSTPIP1-associated myeloid-related proteinemia inflammatory syndrome
Kod ORPHA
251523
Kod OMIM
194470
Kod ICD10
E83.2
Kod ICD11
-

No additional description.

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