Charcot-Marie-Tooth disease type 2B5

Orpha code: 228374OMIM code: 607734

Definition

A rare axonal hereditary motor and sensory neuropathy characterized by infantile onset of slowly progressive distal motor weakness and atrophy (more severe in legs and moderate in arms) with mildly delayed motor development, hypotonia, and distal sensory impairment of all sensory modalities.

Disease data
Classification

Disease

Synonyms
AR-CMT2B5
Ciężka neuropatia aksonalna o wczesnym początku z powodu niedoboru podjednostki lekkich neurofilamentów
Autosomal recessive Charcot-Marie-Tooth disease type 2B5
SEOAN due to NEFL deficiency
Severe early-onset axonal neuropathy due to NEFL deficiency
Severe early-onset axonal neuropathy due to light neurofilament subunit deficiency
ORPHA code
228374
OMIM code
607734
ICD10 code
G60.0
ICD11 code
8C20.1

No additional description.

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