Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare, non-syndromic, hereditary palmoplantar keratoderma characterized by diffuse, yellowish, thick hyperkeratosis of the palms and soles with a sharp demarcation at the volar border and an erythematous margin, and the epidermolytic pattern of changes on the skin biopsy, including perinuclear vacuolization, granular degeneration of keratinocytes in the spinous and granular layer, and tonofilament aggregates. Painful fissures and hyperhidrosis are frequently associated. Disease data Classification Disease Synonyms Diffuse erythrodermic palmoplantar keratoderma, Voerner type Epidermolityczny rogowiec dłoni i stóp Voerner Epidermolityczny rogowiec dłoni i stóp Vörnera EPPK Rozlany erytrodermalny rogowiec dłoni i stóp, typu Voernera Rozlany erytrodermalny rogowiec dłoni i stóp, typu Vörnera Diffuse erythrodermic palmoplantar keratoderma, Vörner type EPPK Epidermolytic palmoplantar keratoderma of Voerner Epidermolytic palmoplantar keratoderma of Vörner ORPHA code 2199 OMIM code 144200 ICD10 code Q82.8 ICD11 code EC20.30 *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl