Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare genetic disease characterized by thickening of the skin on palms and soles restricted to areas of weight bearing and/or friction (focal, non-epidermolytic palmoplantar keratoderma) and oral and esophageal leukokeratosis, associated with a very high lifetime risk of developing squamous cell carcinoma of the esophagus. The skin lesions appear in childhood and can be complicated by fissuring and infection. Disease data Classification Disease Synonyms Bennion-Patterson syndrome Hiperkeratoza dłoni i stóp - rak przełyku Keratosis palmoplantaris-esophageal carcinoma syndrome Zespół Benniona i Pattersona Zespół hiperkeratozy dłoni i stóp oraz nowotworu przełyku Zespół Howella i Evansa Howell-Evans syndrome Keratosis palmoplantaris-esophageal carcinoma syndrome Palmoplantar hyperkeratosis-esophageal carcinoma syndrome Tylosis-oesophageal carcinoma syndrome ORPHA code 2198 OMIM code 148500 ICD10 code Q82.8 ICD11 code EC20.31 *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl