Immune-mediated necrotizing myopathy

Orpha code: 206569OMIM code:

Definition

A rare form of idiopathic inflammatory myopathy characterized by acute or subacute, severe, symmetrical, proximal muscle weakness usually associated with muscle-specific antibodies (anti-HMGCR or anti-SRP). Histopathological characteristics include myocyte necrosis and regeneration without significant inflammation, and C5b-9 deposition on non-necrotic myofibers.

Disease data
Classification

Disease

Synonyms
Anti-HMG-CoA myopathy
NAM
IMNM
Miopatia anty-SRP
Miopatia anty-HMG-CoA
Autoimmunologiczne martwicze zapalenie mięsni
Miopatia immunologiczna z martwicą miocytów
Anti-SRP myopathy
Autoimmune necrotizing myositis
IMNM
Immune myopathy with myocyte necrosis
NAM
ORPHA code
206569
OMIM code
-
ICD10 code
G72.4
ICD11 code
-

No additional description.

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