Primary cutaneous diffuse large B-cell lymphoma, leg type

Orpha code: 178544OMIM code:

Definition

A rare, aggressive, primary cutaneous B-cell lymphoma characterized by rapidly progressive, red to bluish, often ulcerating, nodular tumors predominantly involving the lower legs. Histology shows sheets of centroblasts and immunoblasts that spare the epidermis, but infiltrate the dermis and subcutaneous tissues, and often disseminate extracutaneously. The neoplastic cells typically express CD20, CD79a, Bcl-2, MUM-1, and FOXP1, but are negative for CD10.

Disease data
Classification

Disease

Synonyms
PCDLBCL,LT
PCDLBCL, LT
ORPHA code
178544
OMIM code
-
ICD10 code
C83.3
ICD11 code
2A81.A

No additional description.

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