Exercise-induced hyperinsulinism

Orpha code: 165991OMIM code: 610021

Definition

A rare form of congenital diazoxide-sensitive diffuse hyperinsulinism characterized by episodes of hypoglycemia induced by exercise due to an inappropriate lactate and pyruvate sensitivity in pancreatic beta-cells. Presentation is of recurring episodes of hypoglycemia associated with elevated insulin levels, within 30 minutes of a short period of anaerobic exercise. The degree of hypoglycemia associated with exercise is variable and is only partially responsive to diazoxide.

Disease data
Classification

Disease

Synonyms
EIHI
EIHI
Hiperinsulinizm z powodu niedoboru SLC16A1
Hiperinsulinizm z powodu niedoboru transportera kwasów monokarboksylowych 1
Hipoglikemia hiperinsilinemiczna wywoływana wysiłkiem
Exercise-induced hyperinsulinemic hypoglycemia
Hyperinsulinism due to SLC16A1 deficiency
Hyperinsulinism due to monocarboxylate transporter 1 deficiency
ORPHA code
165991
OMIM code
610021
ICD10 code
E16.1
ICD11 code
5A45

No additional description.

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