Autosomal dominant spastic paraplegia type 17

Orpha code: 100998OMIM code: 270685

Definition

A complex hereditary spastic paraplegia characterized by progressive spastic paraplegia, upper and lower limb muscle atrophy, hyperreflexia, extensor plantar responses, pes cavus and occasionally impaired vibration sense. Association with hand muscles amyotrophy typical.

Disease data
Classification

Disease

Synonyms
SPG17
SPG17
Zespół Silvera
Paraplegia spastyczna-amiotrofia dłoni i stóp
Silver syndrome
Spastic paraplegia-amyotrophy of hands and feet
ORPHA code
100998
OMIM code
270685
ICD10 code
G11.4
ICD11 code
-

No additional description.

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