ACTH-dependent Cushing syndrome

Orpha code: 99892OMIM code:

Definition

A form of endogenous Cushing syndrome (CS) caused by abnormal production of ACTH due, in 80% of cases, to adrenocorticotropic hormone (ACTH) oversecretion by a pituitary adenoma (Cushing disease, CD) and in 20% of cases to ectopic ACTH secretion (CS due to EAS) by an extrapituitary tumor (in 50% of cases originating in the lungs or less commonly in the thymus, pancreas, adrenal gland or thyroid) or very rarely due to a tumor secreting both ACTH and corticotrophin-releasing hormone (CRH).

Disease data
Classification

Clinical group

Synonyms
ACTH-dependent CS
CS zależny od ACTH
Zespół Cushinga zależny od hormonu adrenokortykotropowego
Zespół Cushinga zależny od kortykotropiny
Adrenocorticotropic hormone-dependent Cushing syndrome
Corticotropin-dependent Cushing syndrome
ORPHA code
99892
OMIM code
-
ICD10 code
E24.0
ICD11 code
-

No additional description.

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