Albinism-deafness syndrome

Orpha code: 998OMIM code: 300700

Definition

A rare disorder characterised by congenital nerve deafness and piebaldness with no ocular albinism. It has been described in one large pedigree. Transmission is X-linked with affected males presenting with profound sensorineural deafness and severe pigmentary abnormalities of the skin, and carrier females presenting with variable hearing impairment without any pigmentary changes. The causative gene has been mapped to Xq26.3-q27.1.

Disease data
Classification

Malformation syndrome

Synonyms
Albinism-hearing loss syndrome
ORPHA code
998
OMIM code
300700
ICD10 code
H90.5
ICD11 code
LD2H.Y

No additional description.

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