Xanthinuria type II

Orpha code: 93602OMIM code: 603592

Definition

Type II xanthinuria, a type of classical xanthinuria (see this term), is a rare autosomal recessive disorder of purine metabolism (see this term) characterized by the deficiency of both xanthine dehydrogenase and aldehyde oxidase, leading to the formation of urinary xanthine urolithiasis and leading, in some patients, to kidney failure. Other less common manifestations include arthropathy, myopathy and duodenal ulcer, while some patients remain asymptomatic.

Disease data
Classification

Etiological subtype

Synonyms
XDH and AOX dual deficiency
Podwójny Niedobór dehydrogenazy ksantynowej i oksydazy aldehydowej ksantyny
Podwójny Niedobór XDH i AOX
Xanthine dehydrogenase and xanthine aldehyde oxidase dual deficiency
ORPHA code
93602
OMIM code
603592
ICD10 code
E79.8
ICD11 code
-

No additional description.

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