Treacher-Collins syndrome

Orpha code: 861OMIM code: 613717

Definition

A rare genetic mandibulofacial dysostosis characterized by bilateral symmetrical oto-mandibular dysplasia including underdeveloped cheekbones (malar hypoplasia), a very small low jaw (micrognathia) and downward-slanting palpebral fissures, coloboma of the lower eyelids, microtia, hearing loss and without abnormalities of the extremities. Intelligence is normal.

Disease data
Classification

Malformation syndrome

Synonyms
Franceschetti-Klein syndrome
Zespół Franceschetti i Kleina
Mandibulofacial dysostosis without limb anomalies
Dyzostoza żuchwowo-twarzowa bez wad kończyn
ORPHA code
861
OMIM code
613717
ICD10 code
Q75.4
ICD11 code
LD2F.16

No additional description.

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