Camptodactyly-tall stature-scoliosis-hearing loss syndrome

Orpha code: 85164OMIM code: 610474

Definicja

Camptodactyly-tall stature-scoliosis-hearing loss syndrome is characterised by camptodactyly, tall stature, scoliosis, and hearing loss (CATSHL). It has been described in around 30 individuals from seven generations of the same family. The syndrome is caused by a missense mutation in the FGFR3 gene, leading to a partial loss of function of the encoded protein, which is a negative regulator of bone growth.

Disease data
Klasyfikacja

Disease

Synonimy
CATSHL syndrome
Zespół CATSHL
Camptodactyly-tall stature-scoliosis-deafness syndrome
Kod ORPHA
85164
Kod OMIM
610474
Kod ICD10
Q87.2
Kod ICD11
-

No additional description.

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