Obesity due to melanocortin 4 receptor deficiency

Orpha code: 71529OMIM code: 618406

Definicja

Melanocortin 4 receptor (MC4R) deficiency is the commonest form of monogenic obesity identified so far. MC4R deficiency is characterised by severe obesity, an increase in lean body mass and bone mineral density, increased linear growth in early childhood, hyperphagia beginning in the first year of life and severe hyperinsulinaemia, in the presence of preserved reproductive function.

Disease data
Klasyfikacja

Etiological subtype

Synonimy
MC4R deficiency
Niedobór MC4R
Kod ORPHA
71529
Kod OMIM
618406
Kod ICD10
E66.8
Kod ICD11
-

No additional description.

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