Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare benign proliferative disorder of the synovial membrane primarily affecting young adults (with a peak age of onset in the second to fourth decade of life) characterized by proliferative, locally invasive tumor-like lesions, usually involving a single joint, tendon sheath or bursa (most commonly the joints of the knee and hip and rarely others such as the ankle, shoulder and temporomandibular joints). It presents with pain and limitation of motion along with swelling, heat and tenderness over the involved joint, eventually leading to arthritic degeneration and significant locomotor deficit, if left untreated. PVNS can recur in patients even after treatment. Disease data Classification Disease Synonyms Diffuse-type GCT GCT typ rozlany Guz olbrzymiokomórkowy ścięgna i błony maziowej Guz olbrzymiokomórkowy typ rozlany TGCT TSGCT Diffuse-type giant cell tumor Pigmented villonodular synovitis TGCT TSGCT ORPHA code 66627 OMIM code - ICD10 code M12.2 ICD11 code XH52J9 *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl