Homocystinuria without methylmalonic aciduria

Orpha code: 622OMIM code: 236270

Definition

Homocystinuria without methylmalonic aciduria is an inborn error of vitamin B12 (cobalamin) metabolism characterized by megaloblastic anemia, encephalopathy and, sometimes, developmental delay, and associated with homocystinuria and hyperhomocysteinemia. There are three types of homocystinuria without methylmalonic aciduria; <i>cblE, cblG</i> and <i>cblD-</i>variant 1 (<i>cblD</i>v1).

Disease data
Classification

Disease

Synonyms
Functional methionine synthase deficiency
Funkcjonalny Niedobór syntazy metioniny
Niedobór metylokobalaminy
Methylcobalamin deficiency
ORPHA code
622
OMIM code
236270
ICD10 code
E72.1
ICD11 code
5C50.B

No additional description.

Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl