Alpha-sarcoglycan-related limb-girdle muscular dystrophy R3

Orpha code: 62OMIM code: 608099

Definition

A subtype of autosomal recessive limb-girdle muscular dystrophy characterized by childhood onset of progressive proximal weakness of the shoulder and pelvic girdle muscles, resulting in difficulty walking, scapular winging, calf hypertrophy and contractures of the Achilles tendon, which lead to a tiptoe gait pattern. Cardiac and respiratory involvement is rare.

Disease data
Classification

Disease

Synonyms
Alpha-sarcoglycan-related LGMD R3
Alfa-sarkoglikanopatia
Dystrofia obręczowo-kończynowa z powodu niedoboru alfa-sarkoglikanu
LGMD2D
Alpha-sarcoglycanopathy
Autosomal recessive limb-girdle muscular dystrophy type 2D
LGMD due to alpha-sarcoglycan deficiency
LGMD type 2D
LGMD2D
Limb-girdle muscular dystrophy due to alpha-sarcoglycan deficiency
Limb-girdle muscular dystrophy type 2D
ORPHA code
62
OMIM code
608099
ICD10 code
G71.0
ICD11 code
8C70.41

No additional description.

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