Keratolytic winter erythema

Orpha code: 50943OMIM code: 148370

Definition

Keratolytic winter erythema is a rare epidermal disease, characterized by recurrent centrifugal palmoplantar peeling and erythema presenting seasonal variation (cold weather). Skin lesions may spread to the dorsum of hands and feet and to the interdigital spaces. Lower legs, knees and thighs may also be involved. Episodes may be preceded by itch and hyperhidrosis. Skin biopsy reveals an epidermal spongiosis with clefting in the stratum corneum, followed by regrowth. Keratolytic winter erythema follows an autosomal dominant mode of transmission.

Disease data
Classification

Disease

Synonyms
Erythrokeratolysis hiemalis
Oudtshoorn disease
Erythrokeratolysis hiemalis
Oudtshoorn disease
ORPHA code
50943
OMIM code
148370
ICD10 code
-
ICD11 code
-

No additional description.

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