Zinc-responsive necrolytic acral erythema

Orpha code: 439196OMIM code:

Definition

A rare skin disease characterized initially by erythematous patches with superficial necrosis, at later stages by hyperkeratotic plaques with a rim of dusky erythema, of exclusively acral distribution with a predilection for the lower extremities, and universal association with hepatitis C virus infection. Patients typically experience pruritus or pain. Serum zinc levels may or may not be decreased, although oral zinc supplementation often improves the condition.

Disease data
Classification

Particular clinical situation in a disease or syndrome

Synonyms
NAE
Martwiczy rumień kończynowy
NAE
Necrolytic acral erythema
ORPHA code
439196
OMIM code
-
ICD10 code
L53.8
ICD11 code
-

No additional description.

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