Acute poisoning by drugs with membrane-stabilizing effect

Orpha code: 43119OMIM code:

Definition

A rare clinical situation characterized by acute, potentially life-threatening toxic effects of drugs acting on voltage-gated sodium or calcium channels, such as tricyclic antidepressants, anticonvulsants, local anesthetics and antiarrhythmics, some beta-blockers, and chloroquine. Clinical manifestations include abnormal ECG findings (intraventricular conduction block with widening of the QRS complex, T wave flattening, prolongation of the QT interval) and variable signs and symptoms depending on the drug, typically involving the cardiovascular and central nervous system, among others.

Disease data
Classification

Particular clinical situation in a disease or syndrome

ORPHA code
43119
OMIM code
-
ICD10 code
-
ICD11 code
-

No additional description.

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