Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome

Orpha code: 415OMIM code: 238970

Definition

A rare, genetic disorder of urea cycle metabolism characterized by either a neonatal-onset with manifestations of lethargy, poor feeding, vomiting and tachypnea or, more commonly, presentations in infancy, childhood or adulthood with chronic neurocognitive deficits, acute encephalopathy and/or coagulation defects or other chronic liver dysfunction.

Disease data
Classification

Disease

Synonyms
HHH syndrome
Niedobór nośnika ornityny
Niedobór ORNT1
Zespół HHH
Zespół potrójnego H
ORNT1 deficiency
Ornithine carrier deficiency
Ornithine translocase deficiency
Triple H syndrome
ORPHA code
415
OMIM code
238970
ICD10 code
E72.4
ICD11 code
5C50.AY

No additional description.

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