DITRA

Orpha code: 404546OMIM code: 614204

Definition

A rare, genetic, autoinflammatory syndrome with immune deficiency disease characterized by recurrent and severe flares of generalized pustular psoriasis associated with high fever, asthenia, and systemic inflammation, due to IL36R antagonist deficiency. Psoriatic nail changes (e.g. pitting and onychomadesis) and ichthyosis may occasionally be associated.

Disease data
Classification

Disease

Synonyms
Deficiency of IL-36R antagonist
Niedobór antagonisty IL-36R
Niedobór IL-36Ra
Deficiency of IL-36Ra
ORPHA code
404546
OMIM code
614204
ICD10 code
L40.1
ICD11 code
-

No additional description.

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