Off-periods in Parkinson disease not responding to oral treatment

Orpha code: 391655OMIM code:

Definition

A rare clinical situation occurring in the context of Parkinson disease characterized by return or worsening of symptoms (including motor and/or non-motor symptoms) under antiparkinsonian therapy. Types of off-periods are Morning Off (experienced before the first dose of the day), Delayed On (occurring more frequently after the first dose of the day or after meals), Wearing Off (end-of-dose deterioration), Sudden Off (sudden transition from on to off), and Dose Failure.

Disease data
Classification

Particular clinical situation in a disease or syndrome

ORPHA code
391655
OMIM code
-
ICD10 code
-
ICD11 code
-

No additional description.

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