Fetal carbamazepine syndrome

Orpha code: 370076OMIM code:

Definicja

Fetal carbamazepine syndrome is a drug-related embryofetopathy that can occur when an embryo/fetus is exposed to carbamazepine and that is characterized by facial dysmorphism, with some similarities to that seen in fetal valproate syndrome (see this term), such as epicanthal folds, upward slanting palpebral fissures, short nose, micrognathia and malar hypoplasia, as well as nail dysplasia and major anomalies including cleft lip/palate, neural tube defects and cardiac anomalies. <i>In utero</i> exposure to carbamazepine, in combination with valproate, has been associated with significant developmental delay (particularly affecting verbal intelligence) and a high rate of congenital anomalies.

Disease data
Klasyfikacja

Malformation syndrome

Kod ORPHA
370076
Kod OMIM
-
Kod ICD10
Q86.8
Kod ICD11
-

No additional description.

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