Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A subtype of Metachromatic leukodystrophy characterized by progressive psychomotor regression with an insidious onset after the age of 16 years, most often beginning with intellectual and behavioral changes, such as memory deficits or emotional instability. The clinical picture is dominated by gradual cognitive, later also motor, decline, taking a protracted course with periods of waxing and waning. Decerebration and death occur within decades after disease onset. Disease data Classification Clinical subtype Synonyms Arylsulfatase A deficiency, adult form MLD, postać dorosła Niedobór arylsulfatazy A, postać dorosła MLD, adult form ORPHA code 309271 OMIM code - ICD10 code E75.2 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl