Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare epidermal disease characterized by multiple, usually asymptomatic, yellowish to flesh colored hyperkeratotic papules and plaques on the palms and soles, with a preference for the palmar and plantar margins. Histological examination shows pronounced orthohyperkeratosis overlying a crateriform depression in the epidermis, with hypergranulosis and mild acanthosis, while elastorrhexis is absent. The lesions appear in the second or third decade of life and gradually increase in number over several years. The condition may be sporadic or familial. Disease data Classification Disease Synonyms PPKP3 without elastoidosis Hiperkertoza dłoniowo-podeszwowa punktowa typu 3 bez elastoidozy PPKP3 bez elastoidozy PPPK3 bez elastoidozy Rogowiec dłoniowo-podeszwowy punktowy typu 3 bez elastoidozy PPPK3 without elastoidosis Punctate palmoplantar hyperkeratosis type 3 without elastoidosis Punctate palmoplantar keratoderma type 3 without elastoidosis ORPHA code 308013 OMIM code - ICD10 code Q82.8 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl