Cyanide-induced parkinsonism-dystonia

Orpha code: 306692OMIM code:

Definition

A rare parkinsonian syndrome due to intoxication which develops in individuals surviving an acute cyanide intoxication episode or due to chronic exposure to small cyanide doses. It presents several weeks after acute exposure with progressive typical clinical features of parkinsonism including bradykinesia, rigidity, dystonia, hypomimia, hypokinetic dysarthria, postural instability and retropulsion but no resting or postural tremor. Brain MRI reveals bilateral lesions in the pallidum, posterior putamen, substantia nigra, subthalamic nucleus, temporal and occipital cortex, and cerebellum.

Disease data
Classification

Disease

ORPHA code
306692
OMIM code
-
ICD10 code
G21.2
ICD11 code
-

No additional description.

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