Description of the disease * EnglishPolish Pobierz sekcję do PDF Definition A rare, genetic pituitary disease characterized by infantile-onset, rapid and excessive acceleration of linear growth and body size due to mixed growth hormone (GH)- and prolactin-secreting adenomas and/or pituitary hyperplasia. Patients present with gigantism and may have associated acromegalic features (e.g. coarse facial features, frontal bossing, prognathism, increased interdental space) as well as marked enlargement of hands and feet, soft tissue swelling, increased appetite and acanthosis nigricans. Disease data Classification Disease Synonyms Familial infantile gigantism Dziedziczny gigantyzm dziecięcy Dziedziczny przerost przysadki Gigantyzm dziecięcy z powodu hiperplazji przysadki X-LAG (Gigantyzm kończyn sprzężony z chromosomem X) Hereditary infantile gigantism Hereditary pituitary hyperplasia Infantile gigantism due to pituitary hyperplasia X-LAG ORPHA code 300373 OMIM code 300942 ICD10 code E22.0 ICD11 code - *Soruce Extended description of the disease Pobierz sekcję do PDF No additional description. Orphanet - interntowa baza danych dotyczących rzadkich chorób i sierochych leków. ©INSERM 1999 - Dostępna na stronie www.orphanet.pl