Autosomal systemic lupus erythematosus

Orpha code: 300345OMIM code: 614420

Definition

Autosomal systemic lupus erythematosus is a rare, genetic, multisystemic, chronic autoimmune disease characterized by the presence of systemic lupus erythematosus symptoms in two or more members of a single family. Patients present a wide spectrum of clinical manifestations, including cutaneous (malar rash, photosensitivity), ocular (keratoconjunctivitis sicca, retinopathy), gastrointestinal (oral ulceration, abdominal pain), cardiac (atherosclerosis, chest pain), pulmonary (serositis, pleurisy), musculoskeletal (arthralgia, myalgia), renal (nephritis, hematuria), obstetrical (increased spontaneous abortions, neonatal lupus), constitutional (fatigue, loss of appetite) and neuropsychiatric (mood and cognitive disorders) involvement, among others.

Disease data
Classification

Disease

Synonyms
Autosomal SLE
Rodzinny SLE
Autosomalny SLE
Rodzinny toczeń rumieniowaty układowy
Familial SLE
Familial systemic lupus erythematosus
ORPHA code
300345
OMIM code
614420
ICD10 code
M32.8
ICD11 code
-

No additional description.

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