Intermittent maple syrup urine disease

Orpha code: 268173OMIM code: 248600

Definition

Intermittent maple syrup urine disease (intermittent MSUD) is a mild form of MSUD (see this term) where patients (when well) are asymptomatic with normal levels of branched-chain amino acids (BCAAs) but with catabolic stress are at risk of acute decompensation with ketoacidosis, which can lead to cerebral edema and coma if untreated.

Disease data
Classification

Clinical subtype

Synonyms
Intermittent BCKD deficiency
Postać przerywana MSUD
Przerywany Niedobór BCKD
Przerywany Niedobór dehydrogenazy ketokwasów rozgałęzionych
Intermittent MSUD
Intermittent branched-chain alpha-ketoacid dehydrogenase deficiency
ORPHA code
268173
OMIM code
248600
ICD10 code
E71.0
ICD11 code
5C50.D0

No additional description.

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