Pyruvate dehydrogenase E3-binding protein deficiency

Orpha code: 255182OMIM code: 245349

Definition

Pyruvate dehydrogenase E3-binding protein deficiency is a rare mild form of pyruvate dehydrogenase deficiency (PDHD, see this term) characterized by variable lactic acidosis and neurological dysfunction.

Disease data
Classification

Clinical subtype

Synonyms
2-oxoglutarate complex deficiency
Dihydrolipoyl dehydrogenase deficiency
Glycine cleavage system L protein deficiency
Niedobór dehydrogenazy lipamidowej
Niedobór diaforazy
Niedobór kompleksu 2-oksoglutarowego
Niedobór kompleksu dehydrogenazy rozgałęzionych łańcuchów alfa-ketokwasów
Niedobór składnika białka X dehydrogenazy pirogronianowej
Niedobór składnika kompleksu E dehydrogenazy pirogronianowej
Branched chain alpha-ketoacid dehydrogenase complex deficiency
Diaphorase deficiency
Dihydrolipoyl dehydrogenase deficiency
Glycine cleavage system L protein deficiency
Lipoamide dehydrogenase deficiency
Pyruvate dehydrogenase complex component E3 deficiency
Pyruvate dehydrogenase protein X component deficiency
ORPHA code
255182
OMIM code
245349
ICD10 code
E74.4
ICD11 code
5C53.02

No additional description.

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