Ankylosing vertebral hyperostosis with tylosis

Orpha code: 2206OMIM code: 106400

Definition

A rare dysostosis with predominant vertebral involvement characterized by paraspinal ligament ossification (most pronounced in the lower thoracic region), osteophytosis, marginal sacroiliac joint sclerosis, and punctate hyperkeratosis on the soles and palms. Patients may be asymptomatic or present mild to moderate back pain. There have been no further descriptions in the literature since 1969.

Disease data
Classification

Malformation syndrome

ORPHA code
2206
OMIM code
106400
ICD10 code
M48.1
ICD11 code
LD24.H

No additional description.

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